The role of cellular prion protein in Alzheimer’s disease
Alzheimer’s disease (AD) is the most prevalent age-related neurodegenerative disease that leads to cognitive impairment and dementia. The major defined pathological hallmark of AD is the accumulation of amyloid beta (Aβ), a neurotoxic peptide, derived from beta and gamma-secretase cleavage of the am...
Main Author: | |
---|---|
Format: | masterThesis |
Language: | eng |
Published: |
2016
|
Subjects: | |
Online Access: | http://hdl.handle.net/10773/15766 |
Country: | Portugal |
Oai: | oai:ria.ua.pt:10773/15766 |