The role of cellular prion protein in Alzheimer’s disease

Alzheimer’s disease (AD) is the most prevalent age-related neurodegenerative disease that leads to cognitive impairment and dementia. The major defined pathological hallmark of AD is the accumulation of amyloid beta (Aβ), a neurotoxic peptide, derived from beta and gamma-secretase cleavage of the am...

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Bibliographic Details
Main Author: Correia, Ângela Patricia da Silva (author)
Format: masterThesis
Language:eng
Published: 2016
Subjects:
Online Access:http://hdl.handle.net/10773/15766
Country:Portugal
Oai:oai:ria.ua.pt:10773/15766