Development of noncytotoxic PLGA nanoparticles to improve the effect of a new inhibitor of p53-MDM2 interaction

One possible approach to overcome solubility complications and enhance the biological activity of drugs is their incorporation into drug delivery systems. Within this scope, several nanosphere and nanocapsule formulations of a new inhibitor of p53-MDM2 interaction (xanthone 1) were developed and the...

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Detalhes bibliográficos
Autor principal: Ana M Paiva (author)
Outros Autores: Rita A Pinto (author), Maribel Teixeira (author), Carlos M Barbosa (author), Raquel T Lima (author), Helena H Vasconcelos (author), Emilia Sousa (author), Madalena Pinto (author)
Formato: article
Idioma:eng
Publicado em: 2013
Assuntos:
Texto completo:https://hdl.handle.net/10216/81211
País:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/81211