Development of noncytotoxic PLGA nanoparticles to improve the effect of a new inhibitor of p53-MDM2 interaction

One possible approach to overcome solubility complications and enhance the biological activity of drugs is their incorporation into drug delivery systems. Within this scope, several nanosphere and nanocapsule formulations of a new inhibitor of p53-MDM2 interaction (xanthone 1) were developed and the...

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Bibliographic Details
Main Author: Ana M Paiva (author)
Other Authors: Rita A Pinto (author), Maribel Teixeira (author), Carlos M Barbosa (author), Raquel T Lima (author), Helena H Vasconcelos (author), Emilia Sousa (author), Madalena Pinto (author)
Format: article
Language:eng
Published: 2013
Subjects:
Medicina básica
Basic medicine
Online Access:https://hdl.handle.net/10216/81211
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/81211

Internet

https://hdl.handle.net/10216/81211

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