Production and purification of pDNA as a biopharmaceutical with application in oncolog

This work reports the development of an upstream and downstream process to recover a model plasmid DNA (pDNA) with potential application in gene therapy, particularly targeting breast cancer. After the pDNA production, aqueous biphasic systems (ABS) were investigated to as a recovery and purificatio...

Full description

Bibliographic Details
Main Author: Pires, Carolina Freitas (author)
Format: masterThesis
Language:eng
Published: 2023
Subjects:
Online Access:http://hdl.handle.net/10773/33026
Country:Portugal
Oai:oai:ria.ua.pt:10773/33026