Production and purification of pDNA as a biopharmaceutical with application in oncolog

This work reports the development of an upstream and downstream process to recover a model plasmid DNA (pDNA) with potential application in gene therapy, particularly targeting breast cancer. After the pDNA production, aqueous biphasic systems (ABS) were investigated to as a recovery and purificatio...

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Detalhes bibliográficos
Autor principal: Pires, Carolina Freitas (author)
Formato: masterThesis
Idioma:eng
Publicado em: 2023
Assuntos:
Texto completo:http://hdl.handle.net/10773/33026
País:Portugal
Oai:oai:ria.ua.pt:10773/33026