REST is a hypoxia-responsive transcriptional repressor

Cellular exposure to hypoxia results in altered gene expression in a range of physiologic and pathophysiologic states. Discrete cohorts of genes can be either up- or down-regulated in response to hypoxia. While the Hypoxia-Inducible Factor (HIF) is the primary driver of hypoxia-induced adaptive gene...

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Bibliographic Details
Main Author: Cavadas, Miguel A. S. (author)
Other Authors: Mesnieres, Marion (author), Crifo, Bianca (author), Manresa, Mario C. (author), Selfridge, Andrew C. (author), Keogh, Ciara E. (author), Fabian, Zsolt (author), Scholz, Carsten C. (author), Nolan, Karen A. (author), Rocha, Liliane M. A. (author), Tambuwala, Murtaza M. (author), Brown, Stuart (author), Wdowicz, Anita (author), Corbett, Danielle (author), Murphy, Keith J. (author), Godson, Catherine (author), Cummins, Eoin P. (author), Taylor, Cormac T. (author), Cheong, Alex (author)
Format: article
Language:eng
Published: 2016
Subjects:
Gene silencing
Transcriptional regulatory elements
Online Access:http://hdl.handle.net/10400.7/702
Country:Portugal
Oai:oai:arca.igc.gulbenkian.pt:10400.7/702

Internet

http://hdl.handle.net/10400.7/702

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