REST is a hypoxia-responsive transcriptional repressor

Cellular exposure to hypoxia results in altered gene expression in a range of physiologic and pathophysiologic states. Discrete cohorts of genes can be either up- or down-regulated in response to hypoxia. While the Hypoxia-Inducible Factor (HIF) is the primary driver of hypoxia-induced adaptive gene...

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Detalhes bibliográficos
Autor principal: Cavadas, Miguel A. S. (author)
Outros Autores: Mesnieres, Marion (author), Crifo, Bianca (author), Manresa, Mario C. (author), Selfridge, Andrew C. (author), Keogh, Ciara E. (author), Fabian, Zsolt (author), Scholz, Carsten C. (author), Nolan, Karen A. (author), Rocha, Liliane M. A. (author), Tambuwala, Murtaza M. (author), Brown, Stuart (author), Wdowicz, Anita (author), Corbett, Danielle (author), Murphy, Keith J. (author), Godson, Catherine (author), Cummins, Eoin P. (author), Taylor, Cormac T. (author), Cheong, Alex (author)
Formato: article
Idioma:eng
Publicado em: 2016
Assuntos:
Gene silencing
Transcriptional regulatory elements
Texto completo:http://hdl.handle.net/10400.7/702
País:Portugal
Oai:oai:arca.igc.gulbenkian.pt:10400.7/702

Texto Completo

http://hdl.handle.net/10400.7/702

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