pH Modulation of efflux pump activity of multi-drug resistant Escherichia coli protection during its passage and eventual colonization of the colon

BACKGROUND: Resistance Nodulation Division (RND) efflux pumps of Escherichia coli extrude antibiotics and toxic substances before they reach their intended targets. Whereas these pumps obtain their energy directly from the proton motive force (PMF), ATP-Binding Cassette (ABC) transporters, which can...

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Detalhes bibliográficos
Autor principal: Martins, Ana (author)
Outros Autores: Spengler, Gabriella (author), Rodrigues, Liliana (author), Viveiros, Miguel (author), Ramos, Jorge (author), Martins, Marta (author), Couto, Isabel (author), Fanning, Séamus (author), Pagès, Jean Marie (author), Bolla, Jean Michel (author), Molnar, Joseph (author), Amaral, Leonard (author)
Formato: article
Idioma:eng
Publicado em: 2021
Assuntos:
Biological Transport
Colon
Drug Resistance, Multiple
Escherichia coli
Hydrogen-Ion Concentration
Microbial Sensitivity Tests
Journal Article
Research Support, Non-U.S. Gov't
Microbiology
Biochemistry, Genetics and Molecular Biology (miscellaneous)
Infectious Diseases
SDG 3 - Good Health and Well-being
Texto completo:http://hdl.handle.net/10362/117219
País:Portugal
Oai:oai:run.unl.pt:10362/117219

Texto Completo

http://hdl.handle.net/10362/117219

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