pH Modulation of efflux pump activity of multi-drug resistant Escherichia coli protection during its passage and eventual colonization of the colon

BACKGROUND: Resistance Nodulation Division (RND) efflux pumps of Escherichia coli extrude antibiotics and toxic substances before they reach their intended targets. Whereas these pumps obtain their energy directly from the proton motive force (PMF), ATP-Binding Cassette (ABC) transporters, which can...

Full description

Bibliographic Details
Main Author: Martins, Ana (author)
Other Authors: Spengler, Gabriella (author), Rodrigues, Liliana (author), Viveiros, Miguel (author), Ramos, Jorge (author), Martins, Marta (author), Couto, Isabel (author), Fanning, Séamus (author), Pagès, Jean Marie (author), Bolla, Jean Michel (author), Molnar, Joseph (author), Amaral, Leonard (author)
Format: article
Language:eng
Published: 2021
Subjects:
Biological Transport
Colon
Drug Resistance, Multiple
Escherichia coli
Hydrogen-Ion Concentration
Microbial Sensitivity Tests
Journal Article
Research Support, Non-U.S. Gov't
Microbiology
Biochemistry, Genetics and Molecular Biology (miscellaneous)
Infectious Diseases
SDG 3 - Good Health and Well-being
Online Access:http://hdl.handle.net/10362/117219
Country:Portugal
Oai:oai:run.unl.pt:10362/117219

Internet

http://hdl.handle.net/10362/117219

Similar Items