Unraveling the neuroprotective role of TUDCA in Parkinson´s disease

Accumulating evidence suggests that mitochondrial dysfunction play a central role in Parkinson’s disease (PD). Evidence is based on the identification of PD-associated mutations in genes that affect mitochondrial function, such as phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK...

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Detalhes bibliográficos
Autor principal: Fonseca, Inês Martins Ribeiro da (author)
Formato: masterThesis
Idioma:eng
Publicado em: 2018
Assuntos:
Parkinson’s disease
mitochondrial dysfunction
TUDCA
mitophagy
biogenesis
Domínio/Área Científica::Engenharia e Tecnologia::Outras Engenharias e Tecnologias
Texto completo:http://hdl.handle.net/10362/31885
País:Portugal
Oai:oai:run.unl.pt:10362/31885

Texto Completo

http://hdl.handle.net/10362/31885

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