Unraveling the neuroprotective role of TUDCA in Parkinson´s disease

Accumulating evidence suggests that mitochondrial dysfunction play a central role in Parkinson’s disease (PD). Evidence is based on the identification of PD-associated mutations in genes that affect mitochondrial function, such as phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK...

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Bibliographic Details
Main Author: Fonseca, Inês Martins Ribeiro da (author)
Format: masterThesis
Language:eng
Published: 2018
Subjects:
Parkinson’s disease
mitochondrial dysfunction
TUDCA
mitophagy
biogenesis
Domínio/Área Científica::Engenharia e Tecnologia::Outras Engenharias e Tecnologias
Online Access:http://hdl.handle.net/10362/31885
Country:Portugal
Oai:oai:run.unl.pt:10362/31885

Internet

http://hdl.handle.net/10362/31885

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