Exploring A1 activation and miR-155 modulation in ALS spinal cord astrocytes

Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disorder, characterized by motor neurons (MN) loss in the brain and spinal cord (SC). Astrocyte reactivity and microglia activation account for neurodegeneration through the release of neurotoxins. Cytokines from activated microglia were sho...

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Bibliographic Details
Main Author: Sequeira, Catarina Antunes (author)
Format: masterThesis
Language:eng
Published: 2021
Subjects:
Astrocyte reactive biomarkers
Inflammatory-microRNAs
Microglial A1-activation
miRNA-155 downregulation
mSOD1 SC astrocytes
Neuroinflammation
Domínio/Área Científica::Engenharia e Tecnologia::Outras Engenharias e Tecnologias
Online Access:http://hdl.handle.net/10362/52581
Country:Portugal
Oai:oai:run.unl.pt:10362/52581

Internet

http://hdl.handle.net/10362/52581

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