Exploring A1 activation and miR-155 modulation in ALS spinal cord astrocytes

Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disorder, characterized by motor neurons (MN) loss in the brain and spinal cord (SC). Astrocyte reactivity and microglia activation account for neurodegeneration through the release of neurotoxins. Cytokines from activated microglia were sho...

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Detalhes bibliográficos
Autor principal: Sequeira, Catarina Antunes (author)
Formato: masterThesis
Idioma:eng
Publicado em: 2021
Assuntos:
Astrocyte reactive biomarkers
Inflammatory-microRNAs
Microglial A1-activation
miRNA-155 downregulation
mSOD1 SC astrocytes
Neuroinflammation
Domínio/Área Científica::Engenharia e Tecnologia::Outras Engenharias e Tecnologias
Texto completo:http://hdl.handle.net/10362/52581
País:Portugal
Oai:oai:run.unl.pt:10362/52581

Texto Completo

http://hdl.handle.net/10362/52581

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