Development of a synthetic route towards N4,N9-disubstituted 4,9-diaminoacridines: On the way to multi-stage antimalarials

A multi-step synthetic route towards N4,N9-disubstituted 4,9-diaminoacridines that, to the best of our knowledge, has no precedence in the literature, has been developed. The target structures are likely to reveal interesting biological activities in the near future, not only due to their mepacrine-...

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Detalhes bibliográficos
Autor principal: Fonte, Mélanie (author)
Outros Autores: Fagundes, Natália (author), Gomes, Ana (author), Ferraz, Ricardo (author), Prudêncio, Cristina (author), Araújo, Maria João (author), Gomes, Paula (author), Teixeira, Cátia (author)
Formato: article
Idioma:eng
Publicado em: 2022
Assuntos:
Acridine
Antimalarial
Heteroaromatic
Heterocyclic chemistry
Mepacrine
Quinacrine
Texto completo:http://hdl.handle.net/10400.22/14182
País:Portugal
Oai:oai:recipp.ipp.pt:10400.22/14182

Texto Completo

http://hdl.handle.net/10400.22/14182

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