Development of a synthetic route towards N4,N9-disubstituted 4,9-diaminoacridines: On the way to multi-stage antimalarials

A multi-step synthetic route towards N4,N9-disubstituted 4,9-diaminoacridines that, to the best of our knowledge, has no precedence in the literature, has been developed. The target structures are likely to reveal interesting biological activities in the near future, not only due to their mepacrine-...

Full description

Bibliographic Details
Main Author: Fonte, Mélanie (author)
Other Authors: Fagundes, Natália (author), Gomes, Ana (author), Ferraz, Ricardo (author), Prudêncio, Cristina (author), Araújo, Maria João (author), Gomes, Paula (author), Teixeira, Cátia (author)
Format: article
Language:eng
Published: 2022
Subjects:
Acridine
Antimalarial
Heteroaromatic
Heterocyclic chemistry
Mepacrine
Quinacrine
Online Access:http://hdl.handle.net/10400.22/14182
Country:Portugal
Oai:oai:recipp.ipp.pt:10400.22/14182

Internet

http://hdl.handle.net/10400.22/14182

Similar Items