Yeast chronological lifespan and proteotoxic stress : is autophagy good or bad

Autophagy, a highly conserved proteolytic mechanism of quality control, is essential for the maintenance of metabolic and cellular homoeostasis and for an efficient cellular response to stress. Autophagy declines with aging and is believed to contribute to different aspects of the aging phenotype. Th...

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Detalhes bibliográficos
Autor principal: Sampaio-Marques, Belém (author)
Outros Autores: Felgueiras, Carolina (author), Silva, Alexandra (author), Rodrigues, Fernando José dos Santos (author), Ludovico, Paula (author)
Formato: article
Idioma:eng
Publicado em: 2011
Assuntos:
Autophagy
Chronological aging
Proteotoxic stress
Ras/cAMP dependent protein kinase
Sch9
Target of rapamycin
Ras/cAMP-dependent protein kinase (protein kinase A)
target of rapamycin (TOR)
Science & Technology
Texto completo:http://hdl.handle.net/1822/17433
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/17433

Texto Completo

http://hdl.handle.net/1822/17433

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