Yeast chronological lifespan and proteotoxic stress : is autophagy good or bad

Autophagy, a highly conserved proteolytic mechanism of quality control, is essential for the maintenance of metabolic and cellular homoeostasis and for an efficient cellular response to stress. Autophagy declines with aging and is believed to contribute to different aspects of the aging phenotype. Th...

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Bibliographic Details
Main Author: Sampaio-Marques, Belém (author)
Other Authors: Felgueiras, Carolina (author), Silva, Alexandra (author), Rodrigues, Fernando José dos Santos (author), Ludovico, Paula (author)
Format: article
Language:eng
Published: 2011
Subjects:
Autophagy
Chronological aging
Proteotoxic stress
Ras/cAMP dependent protein kinase
Sch9
Target of rapamycin
Ras/cAMP-dependent protein kinase (protein kinase A)
target of rapamycin (TOR)
Science & Technology
Online Access:http://hdl.handle.net/1822/17433
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/17433

Internet

http://hdl.handle.net/1822/17433

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