Upstream Open Reading Frames and Human Genetic Disease

Abstract: In many eukaryotic messenger ribonucleic acids (mRNAs) one or more short upstream open reading frames (uORFs) precede the initiation codon of the main coding region. For example, in human cells, uORFs are present in about half of the transcripts. Emerging ribosome profiling and peptidomics...

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Detalhes bibliográficos
Autor principal: Barbosa, Cristina (author)
Outros Autores: Onofre, Claudia (author), Romão, Luísa (author)
Formato: bookPart
Idioma:eng
Publicado em: 2015
Assuntos:
Genómica Funcional e Estrutural
Upstream Open Reading Frame (uORF)
Protein Synthesis
Polypeptide
Translational Control
Gene Expression Regulation
Human Genetic Disease
Doenças Genéticas
Texto completo:http://hdl.handle.net/10400.18/2749
País:Portugal
Oai:oai:repositorio.insa.pt:10400.18/2749

Texto Completo

http://hdl.handle.net/10400.18/2749

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