Multidimensional Drug Design: Simultaneous Analysis of Binding and Relative Efficacy Profiles of N6-substituted-4¢-thioadenosines A3 Adenosine Receptor Agonists

Desirability theory (DT) is a well-known multi-criteria decision-making approach. In this work, DT is employed as a prediction model (PM) interpretation tool to extract useful information on the desired trade-offs between binding and relative efficacy of N6-substituted-4¢-thioadenosines A3 adenosine...

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Bibliographic Details
Main Author: Maykel Cruz-Monteagudo (author)
Other Authors: M. Natália D. S. Cordeiro (author), Marta Teijeira (author), Maykel P. González (author), Fernanda Borges (author)
Format: article
Language:eng
Published: 2010
Subjects:
Neuroquímica, Química aplicada, Engenharia química
Neurochemistry, Applied chemistry, Chemical engineering
Online Access:https://hdl.handle.net/10216/96209
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/96209

Internet

https://hdl.handle.net/10216/96209

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