Multidimensional Drug Design: Simultaneous Analysis of Binding and Relative Efficacy Profiles of N6-substituted-4¢-thioadenosines A3 Adenosine Receptor Agonists

Desirability theory (DT) is a well-known multi-criteria decision-making approach. In this work, DT is employed as a prediction model (PM) interpretation tool to extract useful information on the desired trade-offs between binding and relative efficacy of N6-substituted-4¢-thioadenosines A3 adenosine...

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Detalhes bibliográficos
Autor principal: Maykel Cruz-Monteagudo (author)
Outros Autores: M. Natália D. S. Cordeiro (author), Marta Teijeira (author), Maykel P. González (author), Fernanda Borges (author)
Formato: article
Idioma:eng
Publicado em: 2010
Assuntos:
Texto completo:https://hdl.handle.net/10216/96209
País:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/96209