The role of septins on synaptic function and on amyloid precursor protein processing

Alzheimer’s disease (AD) is a most devasting form of neurodegenerative disorders, pathologically characterized by neuronal cell degeneration and death, extracellular senile plaques containing amyloid beta (Aβ) and intra-cellular neurofibrillary tangles composed by hyperphosphorylated tau pro-tein. A...

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Bibliographic Details
Main Author: Ferreira, Catarina B. (author)
Format: doctoralThesis
Language:eng
Published: 2022
Subjects:
Doença de Alzheimer
processamento APP
geração amiloide beta
BDNF
plasticidade sináptica
libertação vesicular
Alzheimer’s disease
amyloid precursor protein processing
Aβ generation
synaptic plasticity
BDNF vesicular release
Domínio/Área Científica::Ciências Médicas::Medicina Básica
Online Access:http://hdl.handle.net/10451/54908
Country:Portugal
Oai:oai:repositorio.ul.pt:10451/54908

Internet

http://hdl.handle.net/10451/54908

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