The role of septins on synaptic function and on amyloid precursor protein processing

Alzheimer’s disease (AD) is a most devasting form of neurodegenerative disorders, pathologically characterized by neuronal cell degeneration and death, extracellular senile plaques containing amyloid beta (Aβ) and intra-cellular neurofibrillary tangles composed by hyperphosphorylated tau pro-tein. A...

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Detalhes bibliográficos
Autor principal: Ferreira, Catarina B. (author)
Formato: doctoralThesis
Idioma:eng
Publicado em: 2022
Assuntos:
Doença de Alzheimer
processamento APP
geração amiloide beta
BDNF
plasticidade sináptica
libertação vesicular
Alzheimer’s disease
amyloid precursor protein processing
Aβ generation
synaptic plasticity
BDNF vesicular release
Domínio/Área Científica::Ciências Médicas::Medicina Básica
Texto completo:http://hdl.handle.net/10451/54908
País:Portugal
Oai:oai:repositorio.ul.pt:10451/54908

Texto Completo

http://hdl.handle.net/10451/54908

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