The role of pfmdr1 in Plasmodium falciparum tolerance to artemether-lumefantrine in Africa

Objective Artemether-lumefantrine (AL), presently the most favoured combination therapy against uncomplicated Plasmodium falciparum malaria in Africa, has recently shown to select for the pfmdr1 86N allele. The objective of this study was to search for the selection of other mutations potentially in...

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Detalhes bibliográficos
Autor principal: Sisowath, Christin (author)
Outros Autores: Ferreira, Pedro E. (author), Bustamante, Leyla Y. (author), Dahlstrom, Sabina (author), Martensson, Andreas (author), Bjorkman, Anders (author), Krishna, Sanjeev (author), Gil, José Pedro (author)
Formato: article
Idioma:eng
Publicado em: 2018
Assuntos:
Sub-Saharan Africa
Mefloquine resistance
Increased sensitivity
Gene
Selection
Malaria
Amplification
Halofantrine
Amodiaquine
Mutations
Texto completo:http://hdl.handle.net/10400.1/11582
País:Portugal
Oai:oai:sapientia.ualg.pt:10400.1/11582

Texto Completo

http://hdl.handle.net/10400.1/11582

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