Functional gallic acid-based dendrimers as synthetic nanotools to remodel amyloid-β-42 into noncytotoxic forms

The self-assembly of amyloid-β (Aβ) generates cytotoxic oligomers linked to the onset and progression of Alzheimer’s disease (AD). As many fundamental molecular pathways that control Aβ aggregation are yet to be unraveled, an important strategy to control Aβ cytotoxicity is the development of bioact...

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Bibliographic Details
Main Author: Araújo, Ana Rita Rodrigues (author)
Other Authors: Correa, Juan (author), Domínguez-Arca, Vicente (author), Reis, R. L. (author), Fernandez-Megia, Eduardo (author), Pires, R. A. (author)
Format: article
Language:eng
Published: 2021
Subjects:
Online Access:http://hdl.handle.net/1822/75096
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/75096