Functional gallic acid-based dendrimers as synthetic nanotools to remodel amyloid-β-42 into noncytotoxic forms

The self-assembly of amyloid-β (Aβ) generates cytotoxic oligomers linked to the onset and progression of Alzheimer’s disease (AD). As many fundamental molecular pathways that control Aβ aggregation are yet to be unraveled, an important strategy to control Aβ cytotoxicity is the development of bioact...

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Detalhes bibliográficos
Autor principal: Araújo, Ana Rita Rodrigues (author)
Outros Autores: Correa, Juan (author), Domínguez-Arca, Vicente (author), Reis, R. L. (author), Fernandez-Megia, Eduardo (author), Pires, R. A. (author)
Formato: article
Idioma:eng
Publicado em: 2021
Assuntos:
Texto completo:http://hdl.handle.net/1822/75096
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/75096