Overactivation of calcineurin induced by amyloid-beta and prion proteins
Amyloid-beta protein (A[beta]) and the scrapie isoform of prion protein (PrPSs) have a central role in the pathogenesis of Alzheimer's disease (AD) and prion-related encephalopathies (PRE), respectively. In both disorders, the deposition of these misfolded proteins is accompanied by apoptotic n...
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| Other Authors: | , , |
| Format: | article |
| Language: | eng |
| Published: |
2008
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| Subjects: | |
| Online Access: | http://hdl.handle.net/10316/4680 |
| Country: | Portugal |
| Oai: | oai:estudogeral.sib.uc.pt:10316/4680 |