Overactivation of calcineurin induced by amyloid-beta and prion proteins
Amyloid-beta protein (A[beta]) and the scrapie isoform of prion protein (PrPSs) have a central role in the pathogenesis of Alzheimer's disease (AD) and prion-related encephalopathies (PRE), respectively. In both disorders, the deposition of these misfolded proteins is accompanied by apoptotic n...
Autor principal: | |
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Outros Autores: | , , |
Formato: | article |
Idioma: | eng |
Publicado em: |
2008
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Assuntos: | |
Texto completo: | http://hdl.handle.net/10316/4680 |
País: | Portugal |
Oai: | oai:estudogeral.sib.uc.pt:10316/4680 |