Genetic and acquired factors that modulate serum bilirubin levels

The isoenzyme UDP-glucuronosyltransferase 1A1 (UGT1A1) catalyzes bilirubin glucuronidation. Molecular studies suggest that the presence of two extra bases in the repetitive promoter TATA box region of the UGT1A1 gene, described as (TA)7 allele, is responsible for the reduced UGT1A1 activity that lea...

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Detalhes bibliográficos
Autor principal: Rodrigues, Carina (author)
Outros Autores: Costa, Elísio (author), Santos-Silva, Alice (author), Santos, Rosário (author), Bronze-da-Rocha, Elsa (author)
Formato: conferenceObject
Idioma:eng
Publicado em: 2012
Assuntos:
Bilirubin
Genetic and aquired factors
UGT1A1
Texto completo:http://hdl.handle.net/10198/7119
País:Portugal
Oai:oai:bibliotecadigital.ipb.pt:10198/7119

Texto Completo

http://hdl.handle.net/10198/7119

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