Genetic and acquired factors that modulate serum bilirubin levels

The isoenzyme UDP-glucuronosyltransferase 1A1 (UGT1A1) catalyzes bilirubin glucuronidation. Molecular studies suggest that the presence of two extra bases in the repetitive promoter TATA box region of the UGT1A1 gene, described as (TA)7 allele, is responsible for the reduced UGT1A1 activity that lea...

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Bibliographic Details
Main Author: Rodrigues, Carina (author)
Other Authors: Costa, Elísio (author), Santos-Silva, Alice (author), Santos, Rosário (author), Bronze-da-Rocha, Elsa (author)
Format: conferenceObject
Language:eng
Published: 2012
Subjects:
Bilirubin
Genetic and aquired factors
UGT1A1
Online Access:http://hdl.handle.net/10198/7119
Country:Portugal
Oai:oai:bibliotecadigital.ipb.pt:10198/7119

Internet

http://hdl.handle.net/10198/7119

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