Role of oxidative stress in ERK and p38 MAPK activation induced by the chemical sensitizer DNFB in a fetal skin dendritic cell line

The intracellular mechanisms involved in the early phase of dendritic cell (DC) activation upon contact with chemical sensitizers are not well known. The strong skin sensitizer 2,4-dinitrofluorobenzene (DNFB) was shown to induce the activation of mitogen-activated protein kinases (MAPK) in DC. In th...

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Bibliographic Details
Main Author: Matos, MT (author)
Other Authors: Duarte, CB (author), Gonçalo, Margarida (author), Lopes, MC (author)
Format: article
Language:eng
Published: 2010
Subjects:
Células Dendríticas
Pele
Dinitrofluorobenzeno
Proteínas Quinases p38 Activadas por Mitógeno
Stress Oxidativo
Online Access:http://hdl.handle.net/10400.4/756
Country:Portugal
Oai:oai:rihuc.huc.min-saude.pt:10400.4/756

Internet

http://hdl.handle.net/10400.4/756

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