Role of oxidative stress in ERK and p38 MAPK activation induced by the chemical sensitizer DNFB in a fetal skin dendritic cell line

The intracellular mechanisms involved in the early phase of dendritic cell (DC) activation upon contact with chemical sensitizers are not well known. The strong skin sensitizer 2,4-dinitrofluorobenzene (DNFB) was shown to induce the activation of mitogen-activated protein kinases (MAPK) in DC. In th...

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Detalhes bibliográficos
Autor principal: Matos, MT (author)
Outros Autores: Duarte, CB (author), Gonçalo, Margarida (author), Lopes, MC (author)
Formato: article
Idioma:eng
Publicado em: 2010
Assuntos:
Células Dendríticas
Pele
Dinitrofluorobenzeno
Proteínas Quinases p38 Activadas por Mitógeno
Stress Oxidativo
Texto completo:http://hdl.handle.net/10400.4/756
País:Portugal
Oai:oai:rihuc.huc.min-saude.pt:10400.4/756

Texto Completo

http://hdl.handle.net/10400.4/756

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