Variational autoencoders and evolutionary algorithms for targeted novel enzyme design

Recent developments in Generative Deep Learning have fostered new engineering methods for protein design. Although deep generative models trained on protein sequence can learn biologically meaningful representations, the design of proteins with optimised properties remains a challenge. We combined d...

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Detalhes bibliográficos
Autor principal: Martins, Miguel (author)
Outros Autores: Rocha, Miguel (author), Pereira, Vítor (author)
Formato: conferencePaper
Idioma:eng
Publicado em: 2022
Assuntos:
Texto completo:https://hdl.handle.net/1822/80098
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/80098