Variational autoencoders and evolutionary algorithms for targeted novel enzyme design

Recent developments in Generative Deep Learning have fostered new engineering methods for protein design. Although deep generative models trained on protein sequence can learn biologically meaningful representations, the design of proteins with optimised properties remains a challenge. We combined d...

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Bibliographic Details
Main Author: Martins, Miguel (author)
Other Authors: Rocha, Miguel (author), Pereira, Vítor (author)
Format: conferencePaper
Language:eng
Published: 2022
Subjects:
Online Access:https://hdl.handle.net/1822/80098
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/80098