Intermediate expression of CCRL1 reveals novel subpopulations of medullary thymic epithelial cells that emerge in the postnatal thymus.

Cortical and medullary thymic epithelial cells (cTECs and mTECs, respectively) provide inductive microenvironments for T-cell development and selection. The differentiation pathway of cTEC/mTEC lineages downstream of common bipotent progenitors at discrete stages of development remains unresolved. U...

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Detalhes bibliográficos
Autor principal: Ribeiro, AR (author)
Outros Autores: Meireles, C (author), Rodrigues, PM (author), Alves, NL (author)
Formato: article
Idioma:eng
Publicado em: 2014
Assuntos:
Animals
Biomarkers/analysis
Cell Differentiation/immunology
Epithelial Cells/cytology
Flow Cytometry
Mice
Mice, Knockout
Oligonucleotide Array Sequence Analysis
Receptors, CCR/biosynthesis
Receptors, CCR/immunology
T-Lymphocytes/cytology
T-Lymphocytes/immunology
Thymus Gland/cytology
Thymus Gland/growth & development
Thymus Gland/immunology
Transcriptome
Texto completo:http://hdl.handle.net/10216/114506
País:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/114506

Texto Completo

http://hdl.handle.net/10216/114506

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