Intermediate expression of CCRL1 reveals novel subpopulations of medullary thymic epithelial cells that emerge in the postnatal thymus.

Cortical and medullary thymic epithelial cells (cTECs and mTECs, respectively) provide inductive microenvironments for T-cell development and selection. The differentiation pathway of cTEC/mTEC lineages downstream of common bipotent progenitors at discrete stages of development remains unresolved. U...

Full description

Bibliographic Details
Main Author: Ribeiro, AR (author)
Other Authors: Meireles, C (author), Rodrigues, PM (author), Alves, NL (author)
Format: article
Language:eng
Published: 2014
Subjects:
Animals
Biomarkers/analysis
Cell Differentiation/immunology
Epithelial Cells/cytology
Flow Cytometry
Mice
Mice, Knockout
Oligonucleotide Array Sequence Analysis
Receptors, CCR/biosynthesis
Receptors, CCR/immunology
T-Lymphocytes/cytology
T-Lymphocytes/immunology
Thymus Gland/cytology
Thymus Gland/growth & development
Thymus Gland/immunology
Transcriptome
Online Access:http://hdl.handle.net/10216/114506
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/114506

Internet

http://hdl.handle.net/10216/114506

Similar Items