Molecular weight of surface immobilized hyaluronic acid infuences CD44-mediated binding of gastric cancer cells

The physiological importance of the interactions between hyaluronic acid (HA) and its main membrane receptor, CD44, in pathological processes, e.g. cancer, is well recognized. However, these interactions are mainly studied in solution, whereas HA in the extracellular matrix (ECM) is partially immobi...

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Bibliographic Details
Main Author: Amorim, Sara (author)
Other Authors: Costa, Diana Pereira Soares (author), Freitas, Daniela (author), Reis, Celso A. (author), Reis, R. L. (author), Pashkuleva, I. (author), Pires, R. A. (author)
Format: article
Language:eng
Published: 2018
Subjects:
CD44
Gastric cancer cells
Hyaluronan
Invadopodia
Layer-by-layer
Science & Technology
Online Access:http://hdl.handle.net/1822/56677
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/56677

Internet

http://hdl.handle.net/1822/56677

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