Evaluating simulated annealing algorithms in the optimization of bacterial strains

In this work, a Simulated Annealing (SA) algorithm is proposed for a Metabolic Engineering task: the optimization of the set of gene deletions to apply to a microbial strain to achieve a desired production goal. Each mutant strain is evaluated by simulating its phenotype using the Flux-Balance Analy...

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Bibliographic Details
Main Author: Rocha, Miguel (author)
Other Authors: Mendes, Rui (author), Maia, Paulo (author), Pinto, José P. (author), Rocha, I. (author), Ferreira, Eugénio C. (author)
Format: conferencePaper
Language:eng
Published: 2007
Subjects:
Simulated annealing
Set based representations
Variable size chromosomes
Metabolic engineering
Flux-balance analysis
Science & Technology
Online Access:https://hdl.handle.net/1822/7473
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/7473

Internet

https://hdl.handle.net/1822/7473

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