Hemolysis of human erythrocytes induced by tamoxifen is related to disruption of membrane structure

Tamoxifen (TAM), the antiestrogenic drug most widely prescribed in the chemotherapy of breast cancer, induces changes in normal discoid shape of erythrocytes and hemolytic anemia. This work evaluates the effects of TAM on isolated human erythrocytes, attempting to identify the underlying mechanisms...

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Detalhes bibliográficos
Autor principal: Cruz Silva, M. M. (author)
Outros Autores: Madeira, Vítor M. C. (author), Almeida, Leonor M. (author), Custódio, José B. A. (author)
Formato: article
Idioma:eng
Publicado em: 2000
Assuntos:
Texto completo:http://hdl.handle.net/10316/5810
País:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/5810