p53 is a key molecular target of ursodeoxycholic acid in regulating apoptosis

p53 plays an important role in regulating expression of genes that mediate cell cycle progression and/or apoptosis. In addition, we have previously shown that the hydrophilic bile acid ursodeoxycholic acid (UDCA) prevents transforming growth factor beta 1-induced p53 stabilization and apoptosis in p...

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Bibliographic Details
Main Author: Amaral, Joana D. (author)
Other Authors: Castro, Rui E. (author), Sola, Susana (author), Steer, Clifford J. (author), Rodrigues, Cecilia M. P. (author)
Format: article
Language:eng
Published: 2015
Subjects:
Biochemistry & Molecular Biology
Online Access:http://hdl.handle.net/10451/21115
Country:Portugal
Oai:oai:repositorio.ul.pt:10451/21115

Internet

http://hdl.handle.net/10451/21115

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