Synthesis and antitumour evaluation of benzopsoralen analogues

The synthesis of five new analogues of benzopsoralens, derived from xanthen-9-one and carbazole is described. The preparation of the hydroxylated precursors, their formylation and the formation of the pyranone ring, by the reaction between ortho-formylated heterocycles and diethyl malonate in EtOH,...

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Bibliographic Details
Main Author: Oliveira, Ana M. A. G. (author)
Other Authors: Campos, Ana M. F. Oliveira (author), Rodrigues, Lígia M. (author), Raposo, M. Manuela M. (author), Machado, António E. H. (author), Nascimento, Maria São José (author), Nazareth, N. (author), Pinto, Madalena (author)
Format: article
Language:eng
Published: 2007
Subjects:
Psoralens
Xanthen-9-one
Carbazole
Antitumour
Coumarin
Science & Technology
Online Access:http://hdl.handle.net/1822/8646
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/8646

Internet

http://hdl.handle.net/1822/8646

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