Metabolic signature of methylone in primary mouse hepatocytes, at subtoxic concentrations

Methylone (3,4-methylenedioxymethcathinone) is one of the most popular new psychoactive drugs worldwide. Although advertised as a safe drug, its use has been associated to several cases of liver damage. In this work, a metabolomics approach based on gas chromatography-mass spectrometry (GC-MS) combi...

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Bibliographic Details
Main Author: Araújo, Ana Margarida (author)
Other Authors: Carvalho, Márcia (author), Bastos, Maria de Lourdes (author), Carvalho, Félix (author), Guedes de Pinho, Paula (author)
Format: article
Language:eng
Published: 2021
Subjects:
Primary mouse hepatocytes
Methylone
Metabolomics
GC–MS
Hepatotoxicity
Intracellular and extracellular metabolite profiling
Online Access:http://hdl.handle.net/10284/9978
Country:Portugal
Oai:oai:bdigital.ufp.pt:10284/9978

Internet

http://hdl.handle.net/10284/9978

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