Structure and conformation of HIV fusion inhibitor peptide T-1249 in presence of model membranes: A molecular dynamics study

Fusion of the HIV envelope with the target cell membrane is a critical step of viral entry into the target cell. Several peptides based on the C-region of HIV gp41 protein have been used in clinical trials as possible HIV fusion inhibitors, this way controlling the progression of the infection. Some...

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Bibliographic Details
Main Author: Martins do Canto, António Manuel teixeira (author)
Other Authors: Carvalho, Alfredo Jorge Palace (author), Ramalho, João Paulo Prates (author), Loura, Luís Miguel Santos (author)
Format: article
Language:por
Published: 2013
Subjects:
Online Access:http://hdl.handle.net/10174/8749
Country:Portugal
Oai:oai:dspace.uevora.pt:10174/8749