pH-sensitive Laponite®/doxorubicin/alginate nanohybrids with improved anticancer efficacy

The efficacy of the anticancer drug doxorubicin (Dox) is limited by an insufficient cellular uptake and drug resistance, which is partially due to ion trapping in acidic environments such as the extracellular environment of solid tumors and the interior of endolysosome vesicles. Herein, we describe...

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Bibliographic Details
Main Author: Gonçalves, Mara (author)
Other Authors: Figueira, Priscilla (author), Maciel, Dina (author), Rodrigues, João (author), Qu, Xue (author), Liu, Changsheng (author), Tomás, Helena (author), Li, Yulin (author)
Format: article
Language:eng
Published: 2019
Subjects:
Alginate
Laponite
Doxorubicin
PH-sensitive nanohybrids
Drug delivery
.
Faculdade de Ciências Exatas e da Engenharia
Online Access:http://hdl.handle.net/10400.13/2419
Country:Portugal
Oai:oai:digituma.uma.pt:10400.13/2419

Internet

http://hdl.handle.net/10400.13/2419

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