pH-sensitive Laponite®/doxorubicin/alginate nanohybrids with improved anticancer efficacy

The efficacy of the anticancer drug doxorubicin (Dox) is limited by an insufficient cellular uptake and drug resistance, which is partially due to ion trapping in acidic environments such as the extracellular environment of solid tumors and the interior of endolysosome vesicles. Herein, we describe...

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Detalhes bibliográficos
Autor principal: Gonçalves, Mara (author)
Outros Autores: Figueira, Priscilla (author), Maciel, Dina (author), Rodrigues, João (author), Qu, Xue (author), Liu, Changsheng (author), Tomás, Helena (author), Li, Yulin (author)
Formato: article
Idioma:eng
Publicado em: 2019
Assuntos:
Alginate
Laponite
Doxorubicin
PH-sensitive nanohybrids
Drug delivery
.
Faculdade de Ciências Exatas e da Engenharia
Texto completo:http://hdl.handle.net/10400.13/2419
País:Portugal
Oai:oai:digituma.uma.pt:10400.13/2419

Texto Completo

http://hdl.handle.net/10400.13/2419

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