Sialyl Tn-Expressing Bladder Cancer Cells Induce a Tolerogenic Phenotype in Innate and Adaptive Immune Cells

Despite the wide acceptance that glycans are centrally implicated in immunity, exactly how they contribute to the tilt immune response remains poorly defined. In this study, we sought to evaluate the impact of the malignant phenotype-associated glycan, sialyl-Tn (STn) in the function of the key orch...

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Bibliographic Details
Main Author: Carrascal, M (author)
Other Authors: Severino, P (author), Cabral, MG (author), Silva, M (author), Ferreira, JA (author), Calais da Silva, F (author), Quinto, H (author), Pen, C (author), Ligeiro, D (author), Lara Santos, L (author), Dall'Olio, F (author), Videira, P (author)
Format: article
Language:eng
Published: 2014
Subjects:
CHLC ANPAT
Antigens, CD44/analysis
Antigens, CD44/immunology
Antigens, Tumor-Associated, Carbohydrate/analysis
Antigens, Tumor-Associated, Carbohydrate/immunology
Cell Line, Tumor
Cells, Cultured
Dendritic Cells/immunology
Dendritic Cells/pathology
Immunity, Innate
Phagocytosis
T-Lymphocytes/immunology
T-Lymphocytes/pathology
Urinary Bladder/immunology
Urinary Bladder/pathology
Urinary Bladder Neoplasms/immunology
Urinary Bladder Neoplasms/pathology
Online Access:http://hdl.handle.net/10400.17/1753
Country:Portugal
Oai:oai:repositorio.chlc.min-saude.pt:10400.17/1753

Internet

http://hdl.handle.net/10400.17/1753

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