New di(hetero)arylethers and di(hetero)arylamines in the thieno[3,2-b]pyridine series: Synthesis, growth inhibitory activity on human tumor cell lines and non-tumor cells, effects on cell cycle and on programmed cell death

New fluorinated and methoxylated di(hetero)arylethers and di(hetero)arylamines were prepared functionalizing the 7-position of the thieno[3,2-blpyridine, using copper (C-O) or palladium (C N) catalyzed couplings, respectively, of the 7-bromothieno[3,2-blpyridine, also prepared, with ortho, meta and...

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Bibliographic Details
Main Author: Queiroz, Maria João R. P. (author)
Other Authors: Peixoto, Daniela (author), Calhelha, Ricardo C. (author), Soares, Pedro (author), dos Santos, Tiago (author), Lima, Raquel T. (author), Campos, Joana F. (author), Abreu, Rui M. V. (author), Ferreira, Isabel C. F. R. (author), Vasconcelos, M. Helena (author)
Format: article
Language:eng
Published: 2013
Subjects:
Di(hetero)arylethers
Di(hetero)arylamines
Thieno[3,2-b]pyridines
Metal-catalyzed couplings
Tumor and non tumor cells growth inhibition
Cell cycle analysis and cell death(NCI-H460)
Cell cycle analysis and cell death
Di(hetero)arylethers Di(hetero)arylamines
Ciências Médicas::Biotecnologia Médica
Science & Technology
Online Access:http://hdl.handle.net/1822/63889
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/63889

Internet

http://hdl.handle.net/1822/63889

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