New di(hetero)arylethers and di(hetero)arylamines in the thieno[3,2-b]pyridine series: Synthesis, growth inhibitory activity on human tumor cell lines and non-tumor cells, effects on cell cycle and on programmed cell death

New fluorinated and methoxylated di(hetero)arylethers and di(hetero)arylamines were prepared functionalizing the 7-position of the thieno[3,2-blpyridine, using copper (C-O) or palladium (C N) catalyzed couplings, respectively, of the 7-bromothieno[3,2-blpyridine, also prepared, with ortho, meta and...

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Detalhes bibliográficos
Autor principal: Queiroz, Maria João R. P. (author)
Outros Autores: Peixoto, Daniela (author), Calhelha, Ricardo C. (author), Soares, Pedro (author), dos Santos, Tiago (author), Lima, Raquel T. (author), Campos, Joana F. (author), Abreu, Rui M. V. (author), Ferreira, Isabel C. F. R. (author), Vasconcelos, M. Helena (author)
Formato: article
Idioma:eng
Publicado em: 2013
Assuntos:
Di(hetero)arylethers
Di(hetero)arylamines
Thieno[3,2-b]pyridines
Metal-catalyzed couplings
Tumor and non tumor cells growth inhibition
Cell cycle analysis and cell death(NCI-H460)
Cell cycle analysis and cell death
Di(hetero)arylethers Di(hetero)arylamines
Ciências Médicas::Biotecnologia Médica
Science & Technology
Texto completo:http://hdl.handle.net/1822/63889
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/63889

Texto Completo

http://hdl.handle.net/1822/63889

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