Hepcidin is regulated by promoter-associated histone acetylation and HDAC3

Hepcidin regulates systemic iron homeostasis. Suppression of hepcidin expression occurs physiologically in iron deficiency and increased erythropoiesis but is pathologic in thalassemia and hemochromatosis. Here we show that epigenetic events govern hepcidin expression. Erythropoiesis and iron defici...

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Detalhes bibliográficos
Autor principal: Pasricha, S. (author)
Outros Autores: Lim, P. (author), Duarte, T. (author), Casu, C. (author), Oosterhuis, D. (author), Mleczko-Sanecka, K. (author), Suciu, M. (author), Da Silva, A. (author), Al-Hourani, K. (author), Arezes, J. (author), McHugh, K. (author), Gooding, S. (author), Frost, J. (author), Wray, K. (author), Santos, A. (author), Porto, G. (author), Repapi, E. (author), Gray, N. (author), Draper, S. (author), Ashley, N. (author), Soilleux, E. (author), Olinga, P. (author), Muckenthaler, M. (author), Hughes, J. (author), Rivella, S. (author), Milne, T. (author), Armitage, A. (author), Drakesmith, H. (author)
Formato: article
Idioma:eng
Publicado em: 2018
Texto completo:http://hdl.handle.net/10400.16/2232
País:Portugal
Oai:oai:repositorio.chporto.pt:10400.16/2232

Texto Completo

http://hdl.handle.net/10400.16/2232

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