A mitochondria-targeted caffeic acid derivative reverts cellular and mitochondrial defects in human skin fibroblasts from male sporadic Parkinson's disease patients

Parkinson's Disease (PD) is a neurodegenerative disorder affecting more than 10 million people worldwide. Currently, PD has no cure and no early diagnostics methods exist. Mitochondrial dysfunction is presented in the early stages of PD, and it is considered an important pathophysiology compone...

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Bibliographic Details
Main Author: Deus, Cláudia M. (author)
Other Authors: Pereira, Susana P. (author), Cunha-Oliveira, Teresa (author), Teixeira, José (author), Simões, Rui F. (author), Cagide, Fernando (author), Benfeito, Sofia (author), Borges, Fernanda (author), Raimundo, Nuno (author), Oliveira, Paulo J. (author)
Format: article
Language:eng
Published: 2021
Subjects:
Human skin fibroblasts
Metabolism
Mitochondria
Mitochondriotropic antioxidant
Sporadic Parkinson's disease
Caffeic Acids
Fibroblasts
Humans
Male
Oxidative Stress
Parkinson Disease
Online Access:http://hdl.handle.net/10316/101011
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/101011

Internet

http://hdl.handle.net/10316/101011

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